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Zygosity, placental membranes and weinberg's rule in a danish consecutive twin series.
By: Husby, H.
Contributor(s): Holm, N. V | Gernow, A.
Subject(s): Zygosity diagnosis | chorionicity | weinberg's rule In: Acta Geneticae Medicae et Gemellologiae: twin research 40(2)Summary: The usual assumption that monochorionic twins are monozygotic has recently been questioned, based on blood group discordance in 3 of 12 monochorionic pairs. Therefore, this study evaluates the validity of zygosity diagnosis based on examination of placental membranes, and at same time evaluates Weinberg's differential rule in a Danish consecutive twin series. All twin pairs, 265 like-sexed and 87 unlike-sexed pairs, born at Odense university hospital, Denmark, from 1 january 1980 through 31 august 1988, were ascertained . In 229 like-sexed pairs, zygosity was determined by serological methods , and in 190 of these, the fetal membranes could be reliably classified. Fiftynine monochorionic twin pairs were indentified and none of those pairs were discordant for any genetic marker.| Item type | Current location | Call number | Status | Date due | Barcode |
|---|---|---|---|---|---|
| Journal | Indira Gandhi Rashtriya Manav Sangrahalaya | Available |
The usual assumption that monochorionic twins are monozygotic has recently been questioned, based on blood group discordance in 3 of 12 monochorionic pairs. Therefore, this study evaluates the validity of zygosity diagnosis based on examination of placental membranes, and at same time evaluates Weinberg's differential rule in a Danish consecutive twin series. All twin pairs, 265 like-sexed and 87 unlike-sexed pairs, born at Odense university hospital, Denmark, from 1 january 1980 through 31 august 1988, were ascertained . In 229 like-sexed pairs, zygosity was determined by serological methods , and in 190 of these, the fetal membranes could be reliably classified. Fiftynine monochorionic twin pairs were indentified and none of those pairs were discordant for any genetic marker.